Differential Induction of Connexins 26 and 30 in Skin Tumors and Their Adjacent Epidermis

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Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis.

Gap junctions (GJs) have been shown to play a role in tumor progression including a variety of keratinocyte-derived and non-keratinocyte-derived skin tumors. Here we show that the synthesis of the GJ proteins connexin 26 and connexin 30 (Cx26 and Cx30) is induced in keratinocyte-derived epithelial skin tumors whereas there is either no change or a downregulation of Cx43. Cx26, Cx30, and Cx43 ar...

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ژورنال

عنوان ژورنال: Journal of Histochemistry & Cytochemistry

سال: 2006

ISSN: 0022-1554,1551-5044

DOI: 10.1369/jhc.5a6719.2005